BMS-1233
BMS-1233 is a potent, orally bioavailable small molecule PD-L1 inhibitor (IC50 = 14.5 nM) . It demonstrates in vitro activity by inducing HepG2 cell death in co-culture with Jurkat T cells and shows in vivo efficacy in mouse melanoma models, supporting its use in immuno-oncology research.
Product Specifications
CAS Number
2447065-99-6
Field of Research
Cell Biology, Immunology & Inflammation
Smiles
N#CC1=CC=CC (=C1) COC2=CC (OCC3=CC=CC (C=4C=CC=CC4) =C3C) =C (Cl) C=C2CN5CCCCC5C (=O) O
Molecular Formula
C35H33ClN2O4
Molecular Weight
581.1
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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