O-Carboranylphenoxyacetanilide
O-Carboranylphenoxyacetanilide is a dual-activity small molecule that inhibits HIF-1α transcriptional activity (IC50: 0.74 μM in HeLa cells) and suppresses HSP60 chaperone and ATPase functions. This compound is a valuable research tool for studying hypoxia signaling and mitochondrial proteostasis in cancer and other disease models.
Product Specifications
CAS Number
2260545-92-2
Field of Research
Epigenetics & Chromatin, Metabolism Research, Signal Transduction
Smiles
O=C (NC1=CC (=CC=C1O) B (O) O) COC2=CC=C (C=C2) C3456[BH]789[BH]%10%11%12[BH]%13%149[BH]%10%15%16[BH]%11%17%18[BH]%1276[BH]%17%195[BH]%20%214[BH]%13%15 ([BH]%148%203) [CH]%16%18%19%21
Molecular Formula
C16H24B11NO5
Molecular Weight
429.29
Storage Conditions
-20°C
Notes
For research use only.
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