JMF4073
JMF4073 is a potent dual inhibitor of TMP and CMP kinases, with IC50 values of 0.16 μM and 0.17 μM, respectively. It demonstrates efficacy against wild-type Bcr-Abl-transformed myeloid cells in both in vitro and in vivo models, supporting its use in oncology research, particularly for studying leukemia cell proliferation and nucleotide metabolism.
Product Specifications
CAS Number
1927930-61-7
Field of Research
Cell Biology, Molecular Biology
Smiles
O=C (OC (C) (C) C) N1CCN (C (=O) CN2SC3=CC=C (F) C=C3C2=O) CC1
Molecular Formula
C18H22FN3O4S
Molecular Weight
395.45
Storage Conditions
-20°C
Notes
For research use only.
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