MRS5663
MRS5663 (Compound 3a) is a potent and selective A3 adenosine receptor (A3AR) agonist with an EC50 of 5.62 nM in β-arrestin2 recruitment assays. It has demonstrated cytoprotective efficacy in preclinical models of skeletal muscle ischemia-reperfusion injury and claudication, supporting research in cardiovascular and metabolic diseases.
Product Specifications
CAS Number
1377272-66-6
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
C (NC) (=O) [C@]12[C@] (C1) ([C@H] ([C@H] (O) [C@@H]2O) N3C=4C (N=C3) =C (NC) N=C (C#CC5=C (Cl) C=CC=C5) N4) [H]
Molecular Formula
C22H21ClN6O3
Molecular Weight
452.89
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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