FLT3/ITD-IN-5
FLT3/ITD-IN-5 (Example 6) is a potent, orally bioavailable dual inhibitor of FLT3 and FLT3-ITD with IC50 values of 0.088 nM and 0.348 nM, respectively. It is a valuable research tool for studying acute myeloid leukemia (AML), enabling both in vitro biochemical assays and in vivo efficacy studies in preclinical models.
Product Specifications
CAS Number
3023632-62-1
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
O=C1C2=NN (C (=C2C=CC3=NNC=4C=CC (=CC34) C=5C=NN (C5OCCN1C) C) CC) C
Molecular Formula
C23H25N7O2
Molecular Weight
431.49
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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