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FLT3/ITD-IN-5

FLT3/ITD-IN-5 (Example 6) is a potent, orally bioavailable dual inhibitor of FLT3 and FLT3-ITD with IC50 values of 0.088 nM and 0.348 nM, respectively. It is a valuable research tool for studying acute myeloid leukemia (AML), enabling both in vitro biochemical assays and in vivo efficacy studies in preclinical models.

Product Specifications

CAS Number

3023632-62-1

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction

Smiles

O=C1C2=NN (C (=C2C=CC3=NNC=4C=CC (=CC34) C=5C=NN (C5OCCN1C) C) CC) C

Molecular Formula

C23H25N7O2

Molecular Weight

431.49

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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