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IGF-1R modulator 1

IGF-1R modulator 1 (Example 5) is a small molecule inhibitor of IGF-1R, FGFR1, TrkA, and TrkB with EC50 values ranging from 0.25 to 0.39 μM. It serves as a research tool for studying neurodegenerative conditions like Alzheimer's disease in both cellular and animal models of impaired neurotrophic signaling.

Product Specifications

CAS Number

2375424-89-6

Field of Research

Cardiovascular Research, Immunology & Inflammation, Signal Transduction

Smiles

O=C1NC (=O) N (C2=CC=C (OC=3C=CC=CC3) C (=C2) C) C (=O) N1C=4C=CC=CC4

Molecular Formula

C22H17N3O4

Molecular Weight

387.39

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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