CDD-1653
CDD-1653 is a potent and selective BMPR2 kinase inhibitor (IC50 = 2.8 nM) that blocks ATP binding, thereby suppressing SMAD1/5/8 phosphorylation and BMP signaling. This tool compound is used in research applications, including in vitro and in vivo studies, investigating diseases linked to dysregulated BMP pathways such as pulmonary arterial hypertension and heterotopic ossification.
Product Specifications
CAS Number
3034216-44-6
Field of Research
Stem Cell & Developmental Biology
Smiles
O=C1N (C=2C=CC=CC2) CCN (C3=NC (=NC=C3OC) NC4=CC=CC (=C4) S (=O) (=O) N) C1
Molecular Formula
C21H22N6O4S
Molecular Weight
454.5
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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