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CDD-1653

CDD-1653 is a potent and selective BMPR2 kinase inhibitor (IC50 = 2.8 nM) that blocks ATP binding, thereby suppressing SMAD1/5/8 phosphorylation and BMP signaling. This tool compound is used in research applications, including in vitro and in vivo studies, investigating diseases linked to dysregulated BMP pathways such as pulmonary arterial hypertension and heterotopic ossification.

Product Specifications

CAS Number

3034216-44-6

Field of Research

Stem Cell & Developmental Biology

Smiles

O=C1N (C=2C=CC=CC2) CCN (C3=NC (=NC=C3OC) NC4=CC=CC (=C4) S (=O) (=O) N) C1

Molecular Formula

C21H22N6O4S

Molecular Weight

454.5

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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