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2G-HaloAUTAC

Compound tt44, a second-generation autophagy-targeting chimera (2G-HaloAUTAC), employs an optimized linker to enhance AUTAC-mediated degradation. It selectively targets and degrades EGFP-HaloTag fusion proteins via autophagy, serving as a valuable tool for probing autophagic pathways in both cellular and in vivo research models.

Product Specifications

CAS Number

2241668-58-4

Field of Research

Cell Biology

Smiles

O=C1N=C (N) NC2=C1N=C (C=3C=NN (C3) CCOCCOCCOCCOCCOCCCCCCCl) N2CC4=CC=C (F) C=C4

Molecular Formula

C31H43ClFN7O6

Molecular Weight

664.17

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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