2G-HaloAUTAC
Compound tt44, a second-generation autophagy-targeting chimera (2G-HaloAUTAC), employs an optimized linker to enhance AUTAC-mediated degradation. It selectively targets and degrades EGFP-HaloTag fusion proteins via autophagy, serving as a valuable tool for probing autophagic pathways in both cellular and in vivo research models.
Product Specifications
CAS Number
2241668-58-4
Field of Research
Cell Biology
Smiles
O=C1N=C (N) NC2=C1N=C (C=3C=NN (C3) CCOCCOCCOCCOCCOCCCCCCCl) N2CC4=CC=C (F) C=C4
Molecular Formula
C31H43ClFN7O6
Molecular Weight
664.17
Storage Conditions
-20°C
Notes
For research use only.
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