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YY173

YY173 is a potent and selective CDK4/6 inhibitor with IC50 values of 7.7 nM and 88 nM, respectively. It demonstrates anti-proliferative activity in Jurkat cells (IC50 = 1.46 μM) and serves as a key precursor for synthesizing PROTAC-based CDK4/6 degraders for cancer research.

Product Specifications

CAS Number

330550-51-1

Field of Research

Cell Biology

Smiles

O=C1C=NC=2C=NC (=NC2N1C3CCCC3) NC4=CC=C (C=C4) N5CCNCC5

Molecular Formula

C21H25N7O

Molecular Weight

391.47

Storage Conditions

-20°C

Notes

For research use only.

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