2-APQC
2-APQC is an orally active, selective SIRT3 agonist (Kd=2.756 μM) that promotes mitochondrial homeostasis. It has demonstrated efficacy in reducing myocardial hypertrophy and fibrosis in both in vivo and in vitro models, making it a valuable tool for studying heart failure and related cardiometabolic diseases.
Product Specifications
CAS Number
500271-63-6
Field of Research
Epigenetics & Chromatin, Molecular Biology
Purity
99.88% (May vary between batches)
Solubility
DMSO:40 mg/mL (98.65 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:2 mg/mL (4.93 mM)
Smiles
O=C (NCCCCC) C=1C=2N=C3C=CC=CC3=NC2N (C1N) CC4=CC=C (F) C=C4
Molecular Formula
C23H24FN5O
Molecular Weight
405.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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