2-APQC
2-APQC is an orally active, selective SIRT3 agonist (Kd=2.756 μM) that promotes mitochondrial homeostasis. It has demonstrated efficacy in reducing myocardial hypertrophy and fibrosis in both in vivo and in vitro models, making it a valuable tool for studying heart failure and related cardiometabolic diseases.
Product Specifications
CAS Number
500271-63-6
Field of Research
Epigenetics & Chromatin, Molecular Biology
Purity
99.88% (May vary between batches)
Solubility
DMSO:40 mg/mL (98.65 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:2 mg/mL (4.93 mM)
Smiles
O=C (NCCCCC) C=1C=2N=C3C=CC=CC3=NC2N (C1N) CC4=CC=C (F) C=C4
Molecular Formula
C23H24FN5O
Molecular Weight
405.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
PB9676-carrier-free 100 µg/Vial
Anti-S100 alpha 6/S100A6 Antibody Picoband® (Carrier-free Conjugate)
Sign In for Pricing
View Details 
bs-8167R-APC-Cy7 100 µL
CHCHD6 Polyclonal Antibody, APC-Cy7 Conjugated
Sign In for Pricing
View Details