VU0448088
VU0448088 (ML253) is a brain-penetrant, positive allosteric modulator of the muscarinic M4 receptor with EC50 values of 56 nM (human) and 176 nM (rat) . This research compound is utilized in preclinical studies investigating potential therapeutic strategies for psychiatric and neurological disorders, including schizophrenia and cognitive deficits.
Product Specifications
CAS Number
1417616-42-2
Field of Research
Neuroscience
Smiles
O=C (NCC=1C=CN=CC1) C=2SC3=NC (=C (Cl) C (=C3C2N) C) C
Molecular Formula
C16H15ClN4OS
Molecular Weight
346.83
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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