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VU0448088

VU0448088 (ML253) is a brain-penetrant, positive allosteric modulator of the muscarinic M4 receptor with EC50 values of 56 nM (human) and 176 nM (rat) . This research compound is utilized in preclinical studies investigating potential therapeutic strategies for psychiatric and neurological disorders, including schizophrenia and cognitive deficits.

Product Specifications

CAS Number

1417616-42-2

Field of Research

Neuroscience

Smiles

O=C (NCC=1C=CN=CC1) C=2SC3=NC (=C (Cl) C (=C3C2N) C) C

Molecular Formula

C16H15ClN4OS

Molecular Weight

346.83

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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