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KRAS G12D inhibitor 24

Compound 103 (KRAS G12D Inhibitor 24) is a potent and orally bioavailable small molecule targeting the KRAS G12D mutation, demonstrating an IC50 of 4 nM. It is a valuable research tool for in vitro biochemical assays and in vivo studies in oncology research, particularly for investigating targeted therapies against pancreatic and colorectal cancers.

Product Specifications

CAS Number

3033701-29-7

Field of Research

Pharmacology & Drug Discovery, Signal Transduction

Smiles

C (#C) C=1C=2C (=CC (O) =CC2C=CC1F) C3=C (F) C4=C (C=N3) C (=NC (OC[C@@]5 (C) \C (=C\F) \CCN (C) C5) =N4) N6CC7NC (C6) CC7

Molecular Formula

C34H33F3N6O2

Molecular Weight

614.66

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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