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Glucocorticoid receptor modulator 4

Compound DL5 (Glucocorticoid receptor modulator 4) is a small molecule conjugate that acts as a glucocorticoid receptor regulator. It demonstrates anti-inflammatory activity, including GRE reporter activation in vitro (EC50 = 40 μM in K562/mTNF cells) and efficacy in mouse arthritis models, supporting research in immunology and inflammation.

Product Specifications

CAS Number

2688785-30-8

Field of Research

Metabolism Research

Smiles

O (C (=O) C1=CC (NC ([C@@H] (NC ([C@@H] (NC (CBr) =O) C) =O) C) =O) =C (F) C=C1) [C@@]2 (C (SCF) =O) [C@]3 (C) [C@@] (C[C@H]2C) ([C@]4 ([C@] (F) ([C@@H] (O) C3) [C@]5 (C) C (CC4) =CC (=O) C=C5) [H]) [H]

Molecular Formula

C37H43BrF3N3O8S

Molecular Weight

826.72

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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