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JANEX-1 hydrochloride

JANEX-1 (WHI-P131) hydrochloride is a selective JAK3 inhibitor with a Ki of 2.3 μM and an IC50 of 78 μM, exhibiting no activity against JAK1 or JAK2. This tool compound is used in vitro and in vivo to investigate JAK3-specific signaling in immunology and autoimmune disease research.

Product Specifications

CAS Number

188829-39-2

Field of Research

Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Smiles

Cl.OC1=CC=C (C=C1) NC=2N=CN=C3C=C (OC) C (OC) =CC32

Molecular Formula

C16H16ClN3O3

Molecular Weight

333.77

Storage Conditions

-20°C

Notes

For research use only.

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