JANEX-1 hydrochloride
JANEX-1 (WHI-P131) hydrochloride is a selective JAK3 inhibitor with a Ki of 2.3 μM and an IC50 of 78 μM, exhibiting no activity against JAK1 or JAK2. This tool compound is used in vitro and in vivo to investigate JAK3-specific signaling in immunology and autoimmune disease research.
Product Specifications
CAS Number
188829-39-2
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Smiles
Cl.OC1=CC=C (C=C1) NC=2N=CN=C3C=C (OC) C (OC) =CC32
Molecular Formula
C16H16ClN3O3
Molecular Weight
333.77
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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