W4022
W4022 (compound 16) is a potent dual G9a/NSD2 methyltransferase inhibitor with IC50 values of 0.241 μM and 0.017 μM, respectively. It demonstrates robust anticancer activity in vitro by inhibiting proliferation, colony formation, and metastasis, and shows significant antitumor efficacy in PANC-1 xenograft models.
Product Specifications
CAS Number
2761292-51-5
Field of Research
Epigenetics & Chromatin
Smiles
N#CC=1N=C2C=C (OCCCN3CCCC3) C (OC) =CC2=C (N1) NC4CCN (CC4) C (C) C
Molecular Formula
C25H36N6O2
Molecular Weight
452.59
Storage Conditions
-20°C
Notes
For research use only.
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