Sp-8-Cl-cAMPS
Sp-8-Cl-cAMPS is a cAMP analog that activates cAKI and cAKII with Ka values of 0.25 μM and 3.2 μM, respectively. It exhibits anti-proliferative activity in vitro against human tumor cell lines, including HL-60 leukemia and LS-174T colon carcinoma cells, with IC50 values ranging from 8 to 100 μM.
Product Specifications
CAS Number
142754-28-7
Field of Research
Signal Transduction
Smiles
ClC=1N (C=2C (N1) =C (N) N=CN2) [C@H]3[C@H] (O) [C@]4 ([C@] (O3) (COP (=O) (S) O4) [H]) [H]
Molecular Formula
C10H11ClN5O5PS
Molecular Weight
379.72
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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