HH0043
HH0043 (Compound 10f) is a potent, orally bioavailable SOS1 inhibitor with an IC50 of 5.8 nM. It is a valuable research tool for investigating KRAS-driven cancers in both cellular assays and animal models.
Product Specifications
CAS Number
2922069-42-7
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
N ([C@H] (C) C1=C (F) C (C (F) F) =CC=C1) C=2C3=C (C=NC (=C3) N4CCN (C (C) =O) CC4) N=CC2
Molecular Formula
C23H24F3N5O
Molecular Weight
443.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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