HbF inducer 2
Compound dWIZ-2 is an orally active PROTAC molecular glue degrader of the WIZ transcription factor (DC50 = 13 nM) . It potently induces fetal hemoglobin (HbF) expression (EC50 = 100 nM) and serves as a valuable research tool for studying hemoglobinopathies like sickle cell disease in both cellular and animal models.
Product Specifications
CAS Number
2654011-51-3
Field of Research
Pharmacology & Drug Discovery
Purity
97.49% (May vary between batches)
Smiles
O=C1N (CC=2C1=CC=C (OC[C@@H]3N (CC) CCCC3) C2) C4C (=O) NC (=O) CC4
Molecular Formula
C21H27N3O4
Molecular Weight
385.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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