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HbF inducer 2

Compound dWIZ-2 is an orally active PROTAC molecular glue degrader of the WIZ transcription factor (DC50 = 13 nM) . It potently induces fetal hemoglobin (HbF) expression (EC50 = 100 nM) and serves as a valuable research tool for studying hemoglobinopathies like sickle cell disease in both cellular and animal models.

Product Specifications

CAS Number

2654011-51-3

Field of Research

Pharmacology & Drug Discovery

Purity

97.49% (May vary between batches)

Smiles

O=C1N (CC=2C1=CC=C (OC[C@@H]3N (CC) CCCC3) C2) C4C (=O) NC (=O) CC4

Molecular Formula

C21H27N3O4

Molecular Weight

385.46

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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