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PARP-1-IN-23

PARP-1-IN-23 (Compound I16) is a potent and selective PARP-1 inhibitor with an IC50 of 12.38 nM, demonstrating oral bioavailability. It is a valuable research tool for investigating DNA damage response pathways and has shown efficacy in suppressing tumor growth in preclinical in vivo models.

Product Specifications

CAS Number

2976497-48-8

Field of Research

Cell Biology, Epigenetics & Chromatin, Molecular Biology

Smiles

O=C (N) C=1C=CC=C2N=C (NC21) C=3C=C (Br) C (OS (=O) (=O) C=4C=CC=CC4C) =C (OC) C3

Molecular Formula

C22H18BrN3O5S

Molecular Weight

516.36

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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