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PSB-KK1445

PSB-KK1445 is a highly selective GPR18 agonist with EC50 values of 45.4 nM (human) and 124 nM (mouse), showing >200-fold selectivity over related receptors GPR55 and GPR183. This tool compound is used in vitro and in vivo to investigate GPR18's role in immune regulation, neuroinflammation, and metabolic processes.

Product Specifications

CAS Number

885896-54-8

Field of Research

Pharmacology & Drug Discovery

Smiles

O=C1C2=C (N=C (NCCC3=CNC=4C=CC=CC43) N2CC5=CC=C (F) C=C5) N (C (=O) N1C) C

Molecular Formula

C24H23FN6O2

Molecular Weight

446.48

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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