PSB-KK1445
PSB-KK1445 is a highly selective GPR18 agonist with EC50 values of 45.4 nM (human) and 124 nM (mouse), showing >200-fold selectivity over related receptors GPR55 and GPR183. This tool compound is used in vitro and in vivo to investigate GPR18's role in immune regulation, neuroinflammation, and metabolic processes.
Product Specifications
CAS Number
885896-54-8
Field of Research
Pharmacology & Drug Discovery
Smiles
O=C1C2=C (N=C (NCCC3=CNC=4C=CC=CC43) N2CC5=CC=C (F) C=C5) N (C (=O) N1C) C
Molecular Formula
C24H23FN6O2
Molecular Weight
446.48
Storage Conditions
-20°C
Notes
For research use only.
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