G9a-IN-2
G9a-IN-2 (Compound 7i) is a potent G9a histone methyltransferase inhibitor (IC50 = 24 nM) . It effectively reduces H3K9me2 levels and induces γ-globin expression in cellular models, showing therapeutic potential for sickle cell disease research through fetal hemoglobin reactivation.
Product Specifications
CAS Number
2648853-26-1
Field of Research
Epigenetics & Chromatin
Smiles
CC=1C2=C (NC1C (N[C@H] (C (NC3=CC=C (OC4CCN (C) CC4) C=C3) =O) CCCC) =O) CC (C) (C) CC2=O
Molecular Formula
C30H42N4O4
Molecular Weight
522.68
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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