Casdatifan
Casdaitifan (AB521) is an orally bioavailable small molecule inhibitor targeting hypoxia-inducible factor 2 alpha (HIF-2α) . It demonstrates potent anti-tumor activity in preclinical models, including in vitro assays and in vivo studies using clear cell renal cell carcinoma (ccRCC) xenografts.
Product Specifications
CAS Number
2709069-30-5
Field of Research
Epigenetics & Chromatin, Metabolism Research
Smiles
C (#N) C1=C2[C@H] (C[C@H] (F) [C@H] (F) C2=CC (F) =C1) C3=C4C (=C (S (C) (=O) =O) C=C3) [C@H] (O) [C@H] (F) C4
Molecular Formula
C21H17F4NO3S
Molecular Weight
439.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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