NDI-101150
NDI-101150 (NMBS-2) is a potent, selective, and orally bioavailable HPK1 inhibitor that blocks BLNK phosphorylation. Its application in cancer research includes investigating mechanisms for enhancing anti-tumor immunity, with studies conducted in both cellular assays and preclinical in vivo models of metastatic solid tumors.
Product Specifications
CAS Number
2628486-22-4
Product Name Alternative
NDI101150, NMBS2, NMBS-2
Field of Research
Signal Transduction
Purity
99.65% (May vary between batches)
Smiles
N (C1=C2C (=C (C=C1) C=3N4C (=NC3) C=C (F) C=C4) CNC2=O) C=5N=C (CN (C) C) C (=CC5) [C@@H]6CCOC6
Molecular Formula
C27H27FN6O2
Molecular Weight
486.54
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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