INHBB, Human (HEK293, His)
The INHBB protein complexly controls pituitary function, regulating follicle-stimulating hormone and activin. Its critical role extends to a variety of physiological processes, including hormone secretion, cell development, insulin release, and bone growth. INHBB Protein, Human (HEK293, His) is the recombinant human-derived INHBB protein, expressed by HEK293 , with C-10*His labeled tag.
Product Specifications
Product Name Alternative
INHBB Protein, Human (HEK293, His), Human, HEK293
UNSPSC
12352202
Type
Recombinant Proteins
Assay Protocol
https://www.medchemexpress.com/cytokines/activin-b-protein-human-hek293-his.html
Purity
97.61
Smiles
SPTPPPTPAAPPPPPPPGSPGGSQDTCTSCGGFRRPEELGRVDGDFLEAVKRHILSRLQMRGRPNITHAVPKAAMVTALRKLHAGKVREDGRVEIPHLDGHASPGADGQERVSEIISFAETDGLASSRVRLYFFISNEGNQNLFVVQASLWLYLKLLPYVLEKGSRRKVRVKVYFQEQGHGDRWNMVEKRVDLKRSGWHTFPLTEAIQALFERGERRLNLDVQCDSCQELAVVPVFVDPGEESHRPFVVVQARLGDSRHRIRKRGLECDGRTNLCCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRGLNPGTVNSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGCA
Molecular Formula
3625 (Gene_ID) P09529/NP_002184.2 (S29-A407) (Accession)
Molecular Weight
Approximately 14-17 kDa (propeptide) & 40-44 kDa (mature form) & 54-58 kDa (proform), based on SDS-PAGE under reducing conditions, due to the glycosylation.
References & Citations
[1]Shi-Kang Deng, et al. Activin B signaling may promote the conversion of normal fibroblasts to scar fibroblasts. Medicine (Baltimore) . 2020 Jun 12;99 (24) :e20253.|[2]J M Young, et al. Activin B is produced early in antral follicular development and suppresses thecal androgen production. Reproduction. 2012 May;143 (5) :637-50.|[3]Siyuan Xiong, et al. Activin B promotes endometrial cancer cell migration by down-regulating E-cadherin via SMAD-independent MEK-ERK1/2-SNAIL signaling. Oncotarget. 2016 Jun 28;7 (26) :40060-40072.|[4]Sabine Gravelsina, et al. Potential of Activin B as a Clinical Biomarker in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) . Biomolecules. 2021 Aug 11;11 (8) :1189.|[5]Qin Jia, et al. Activin B promotes initiation and development of hair follicles in mice. Cells Tissues Organs. 2013;198 (4) :318-26.
Shipping Conditions
Room temperature in continental US; may vary elsewhere.
Storage Conditions
Stored at -20°C for 2 years
Scientific Category
Recombinant Proteins
Available Sizes
Frequently Asked Questions
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