TH7127
TH7127 is a selective SAMHD1 inhibitor that blocks its enzymatic hydrolysis of nucleotide analogs such as ara-CTP and Cl-F-ara-ATP. This small molecule is a valuable research tool for investigating SAMHD1's role in nucleotide metabolism and resistance mechanisms in cancer and virology, applicable in both cellular and biochemical assays.
Product Specifications
Product Name Alternative
TH7 127, TH7127, TH7-127, SAMHD1
Purity
98.89% (May vary between batches)
Solubility
DMSO:100 mg/mL (289.52 mM) ; H2O:< 1 mg/mL (insoluble)
Smiles
COc1ccccc1-c1cn2ccnc2c (NCCc2ccccn2) n1
Molecular Formula
C20H19N5O
Molecular Weight
345.4
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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