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TH7127

TH7127 is a selective SAMHD1 inhibitor that blocks its enzymatic hydrolysis of nucleotide analogs such as ara-CTP and Cl-F-ara-ATP. This small molecule is a valuable research tool for investigating SAMHD1's role in nucleotide metabolism and resistance mechanisms in cancer and virology, applicable in both cellular and biochemical assays.

Product Specifications

Product Name Alternative

TH7 127, TH7127, TH7-127, SAMHD1

Purity

98.89% (May vary between batches)

Solubility

DMSO:100 mg/mL (289.52 mM) ; H2O:< 1 mg/mL (insoluble)

Smiles

COc1ccccc1-c1cn2ccnc2c (NCCc2ccccn2) n1

Molecular Formula

C20H19N5O

Molecular Weight

345.4

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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