SAG
(Rac) -SAG is a potent and selective Smoothened (Smo) agonist (EC50 = 3 nM) that activates Hedgehog signaling. It is widely used in biochemical and cellular assays to study pathway mechanisms and has been applied in vivo to explore tissue regeneration and oncogenesis models.
Product Specifications
CAS Number
364590-63-6
Product Name Alternative
Smoothened Agonist
Field of Research
Neuroscience
Purity
>98%
Bioactivity
Smoothened agonist
Form
Powder
Solubility
Soluble in DMSO (up to 20 mg/ml), in DMF (up to 20 mg/ml) or in Ethanol (up to 20 mg/ml) .
Smiles
N (C (=O) C1=C (Cl) C=2C (S1) =CC=CC2) (CC3=CC (=CC=C3) C=4C=CN=CC4) C5CCC (NC) CC5
Molecular Formula
C28H28ClN3OS
Molecular Weight
490.07
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
3-Chloro-N-[trans-4- (methylamino) cyclohexyl]-N-[[3- (4-pyridinyl) phenyl]methyl]-benzo[b]thiiophene-2-carboxamide dihydrochloride
Available Sizes
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