5-HT2CR agonist 1

This 7-chloro analogue is a selective 5-HT2C receptor partial agonist (Emax 71.09%, EC50 121.5 nM) with no activity at 5-HT2A/2B receptors, no β-arrestin recruitment, and low hERG inhibition. It is a valuable research tool for studying 5-HT2C function in neuropsychiatric and metabolic disorders, suitable for in vitro signaling assays.