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AB-452

AB-452 is a dihydroquinolizinone-based, orally bioavailable small molecule that acts as a potent PAPD5/7 inhibitor. It destabilizes HBV RNA in vitro and has shown efficacy in a chronic HBV mouse model, making it a useful research tool for investigating novel antiviral strategies against hepatitis B.

Product Specifications

CAS Number

2226178-35-2

Field of Research

Infectious Disease & Virology

Smiles

[C@@H] (C) (C) [C@H]1N2C (C=3C (C1) =CC (OCCCOC) =C (OC) N3) =CC (=O) C (C (O) =O) =C2

Molecular Formula

C21H26N2O6

Molecular Weight

402.44

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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