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Akt1-IN-3

Akt1-IN-3 (Compound 7) is a potent and selective small-molecule inhibitor of the AKT1-E17K mutant, demonstrating an IC50 below 15 nM. This inhibitor is a valuable research tool for studying oncogenic AKT signaling in cancer biology, applicable in both in vitro cellular assays and in vivo model studies.

Product Specifications

CAS Number

3033576-50-7

Field of Research

Signal Transduction

Smiles

O=CC1=CC (=CC=C1O) C (=O) NC2CCN (CC3=CC=C (C=C3) N4C=5N=C (C=CC5N=C4C6=CC=CN=C6N) C=7C=CC=CC7) CC2

Molecular Formula

C37H33N7O3

Molecular Weight

623.70

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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