Akt1-IN-3
Akt1-IN-3 (Compound 7) is a potent and selective small-molecule inhibitor of the AKT1-E17K mutant, demonstrating an IC50 below 15 nM. This inhibitor is a valuable research tool for studying oncogenic AKT signaling in cancer biology, applicable in both in vitro cellular assays and in vivo model studies.
Product Specifications
CAS Number
3033576-50-7
Field of Research
Signal Transduction
Smiles
O=CC1=CC (=CC=C1O) C (=O) NC2CCN (CC3=CC=C (C=C3) N4C=5N=C (C=CC5N=C4C6=CC=CN=C6N) C=7C=CC=CC7) CC2
Molecular Formula
C37H33N7O3
Molecular Weight
623.70
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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