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AMPK activator 14

AMPK activator 14 (compound 32) is an orally bioavailable small molecule that demonstrates efficacy in a Type II diabetes model by lowering both glucose and insulin levels in fasted db/db mice. This tool compound is suitable for investigating AMPK pathway biology in metabolic disease research, including in vitro mechanistic studies and in vivo pharmacological evaluations.

Product Specifications

CAS Number

1356632-18-2

Field of Research

Epigenetics & Chromatin, Signal Transduction

Smiles

C (=O) (N1CCC (C (=O) C2=CC=C (OC) C=C2) CC1) C3=CC=C (C (N[C@@H]4[C@@H] (F) CN (CC5=CC=C (C#N) C=C5) CC4) =O) C=N3

Molecular Formula

C33H34FN5O4

Molecular Weight

583.65

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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