Anti-infective agent 9
Anti-infective agent 9 is a metabolically stable small molecule inhibitor of Plasmodium falciparum (IC50 = 600 nM) . It disrupts parasite energy metabolism by lowering pyruvate and impairing the TCA cycle, showing low hepatotoxicity. This compound is a valuable tool for studying novel antimalarial pathways in vitro, excluding DXPS as a target.
Product Specifications
CAS Number
758689-17-7
Field of Research
Infectious Disease & Virology
Smiles
FC (F) (F) C1=CC=C (C=C1) NC2=NC (=CS2) C=3SC (=NC3C) N
Molecular Formula
C14H11F3N4S2
Molecular Weight
356.39
Storage Conditions
-20°C
Notes
For research use only.
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