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Antimalarial agent 36

This potent antimalarial small molecule, known as compound 1, demonstrates high efficacy with EC50 values of 58 nM (Dd2) and 42 nM (3D7) . It functions as a specific EphA2 kinase inhibitor, making it a valuable tool for investigating host-targeted antimalarial strategies in both in vitro and in vivo research contexts.

Product Specifications

CAS Number

2982633-03-2

Field of Research

Infectious Disease & Virology

Smiles

O=C (NC1=CC (Cl) =CC (=C1) C (=O) NC2=CC=C (C (=C2) C (F) (F) F) CN3CCN (CC) CC3) C4=CN=CC (=C4) C=5SC=CC5

Molecular Formula

C31H29ClF3N5O2S

Molecular Weight

628.11

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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