AR/AR-V7-IN-1
AR/AR-V7-IN-1 (Compound 20i) is a small molecule inhibitor of the androgen receptor and its splice variant AR-V7, with an IC50 of 172.85 nM. It demonstrates anti-proliferative activity in LNCaP and 22RV1 prostate cancer cell lines and has shown efficacy in inhibiting tumor growth in a 22RV1 xenograft model, supporting its use in prostate cancer research.
Product Specifications
CAS Number
2964558-54-9
Field of Research
Metabolism Research
Smiles
N (C1CN (CCCF) C1) C2=CC=C (CC3CCN (CC3) C4=CC=C (C (N[C@@H]5CC[C@@H] (OC6=CC (Cl) =C (C#N) C=C6) CC5) =O) N=N4) C=C2
Molecular Formula
C36H43ClFN7O2
Molecular Weight
660.22
Storage Conditions
-20°C
Notes
For research use only.
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