ARI-3144
ARI-3144 is a fibroblast activation protein (FAP) -activated small molecule proteasome inhibitor. This prodrug strategy enables targeted inhibition of proteasome activity within the tumor microenvironment, making it a valuable tool for investigating solid tumor biology in both cellular and animal models.
Product Specifications
CAS Number
1426305-25-0
Field of Research
Protein Biochemistry
Smiles
C (N[C@@H] (C (=O) N1[C@H] (C (NC=2C=C3C (=CC2) C (C) =CC (=O) O3) =O) CCC1) C) (=O) C=4C5=C (N=CC4) C=CC=C5
Molecular Formula
C28H26N4O5
Molecular Weight
498.53
Storage Conditions
-20°C
Notes
For research use only.
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