ARN22089
ARN22089 is an orally bioavailable small molecule inhibitor targeting the CDC42 GTPase interaction. It demonstrates in vivo efficacy by suppressing tumor growth in BRAF-mutant melanoma, as validated in mouse models and patient-derived xenografts (PDXs) . This inhibitor is a valuable research tool for studying oncogenic signaling pathways in both cellular and animal studies.
Product Specifications
CAS Number
2248691-29-2
Product Name Alternative
ARN 22089
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Purity
98.37% (May vary between batches)
Smiles
N=1C (=CC (=NC1C2CCNCC2) C=3C=CC=CC3) NC4=CC=CC (=C4) N (C) C
Molecular Formula
C23H27N5
Molecular Weight
373.49
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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