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AZ760

AZ760 is a potent and lipophilic small molecule CCR8 antagonist with high unbound plasma concentration, suitable for in vitro binding and cellular chemotaxis assays. However, its development for in vivo research is limited by significant hERG channel inhibition, a known cardiac safety concern.

Product Specifications

CAS Number

912461-36-0

Field of Research

Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery

Smiles

O=C (C=1C=CC=CN1=O) N2CCC3 (CC2) CCN (CC=4C=CC=CC4OC=5C=CC=CC5OC) CC3

Molecular Formula

C29H33N3O4

Molecular Weight

487.59

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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