AZ760
AZ760 is a potent and lipophilic small molecule CCR8 antagonist with high unbound plasma concentration, suitable for in vitro binding and cellular chemotaxis assays. However, its development for in vivo research is limited by significant hERG channel inhibition, a known cardiac safety concern.
Product Specifications
CAS Number
912461-36-0
Field of Research
Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery
Smiles
O=C (C=1C=CC=CN1=O) N2CCC3 (CC2) CCN (CC=4C=CC=CC4OC=5C=CC=CC5OC) CC3
Molecular Formula
C29H33N3O4
Molecular Weight
487.59
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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