BET-IN-20
BET-IN-20 is a potent and selective BRD4 BD1 inhibitor (IC50=1.9 nM) with anticancer activity. It induces apoptosis and G0/G1 cell cycle arrest in AML cells by suppressing c-Myc and CDK6, while enhancing PARP cleavage, as demonstrated in vitro.
Product Specifications
CAS Number
1300735-76-5
Field of Research
Cell Biology, Epigenetics & Chromatin
Smiles
[C@H] (C) (N1C=2C=3C (=CC (=C (OC) C3) C=4C (C) =NOC4C) N=CC2N=C1C) C5=CC=CC=C5
Molecular Formula
C25H24N4O2
Molecular Weight
412.48
Storage Conditions
-20°C
Notes
For research use only.
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