BET-IN-20
BET-IN-20 is a potent and selective BRD4 BD1 inhibitor (IC50=1.9 nM) with anticancer activity. It induces apoptosis and G0/G1 cell cycle arrest in AML cells by suppressing c-Myc and CDK6, while enhancing PARP cleavage, as demonstrated in vitro.
Product Specifications
CAS Number
1300735-76-5
Field of Research
Cell Biology, Epigenetics & Chromatin
Smiles
[C@H] (C) (N1C=2C=3C (=CC (=C (OC) C3) C=4C (C) =NOC4C) N=CC2N=C1C) C5=CC=CC=C5
Molecular Formula
C25H24N4O2
Molecular Weight
412.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
251148-HRP 100 µL
RIPK4 (Receptor-Interacting Serine-Threonine Kinase 4, ANKK2, ANKRD3, DIK, MGC129992, MGC129993, PKK, RIP4) (HRP)
Sign In for Pricing
View Details 
MBS6266725-01 0.1 mL
c-erbB2, mixed clones (HER-2, neu Receptor) (BSA & Azide Free) (HRP)
Sign In for Pricing
View Details MBS6266725-02 5x 0.1 mL
c-erbB2, mixed clones (HER-2, neu Receptor) (BSA & Azide Free) (HRP)
Sign In for Pricing
View Details