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BET-IN-23

BET-IN-23 is a potent and selective BD2-targeting BET inhibitor (IC50 = 2.9 nM) . It demonstrates anti-leukemic activity in vitro by suppressing AML cell proliferation, inducing cell cycle arrest and apoptosis. Its research applications include epigenetic and cancer biology studies, with potential for in vivo efficacy investigation.

Product Specifications

CAS Number

2953287-57-3

Field of Research

Cell Biology, Epigenetics & Chromatin

Smiles

O (C1=C (C=C (C (C) (C) O) C=C1) C=2C (NCC (=O) N3CCOCC3) =CC (=O) N (C) C2) C4=C (C) C=C (F) C=C4C

Molecular Formula

C29H34FN3O5

Molecular Weight

523.60

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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