BET-IN-23
BET-IN-23 is a potent and selective BD2-targeting BET inhibitor (IC50 = 2.9 nM) . It demonstrates anti-leukemic activity in vitro by suppressing AML cell proliferation, inducing cell cycle arrest and apoptosis. Its research applications include epigenetic and cancer biology studies, with potential for in vivo efficacy investigation.
Product Specifications
CAS Number
2953287-57-3
Field of Research
Cell Biology, Epigenetics & Chromatin
Smiles
O (C1=C (C=C (C (C) (C) O) C=C1) C=2C (NCC (=O) N3CCOCC3) =CC (=O) N (C) C2) C4=C (C) C=C (F) C=C4C
Molecular Formula
C29H34FN3O5
Molecular Weight
523.60
Storage Conditions
-20°C
Notes
For research use only.
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