BIO-7488
BIO-7488 is a highly potent and selective IRAK4 inhibitor with an IC50 of 0.6 nM, demonstrating oral bioavailability and central nervous system penetration. Its utility in researching neuroinflammatory and autoimmune diseases is supported by its favorable selectivity profile over hERG (>30 μM) for in vitro and in vivo experimental models.
Product Specifications
CAS Number
2573211-25-1
Field of Research
Immunology & Inflammation, Signal Transduction
Smiles
CC12CC (C1) (CO2) C=3N=C4N (C3) C=C (C (NC5=C6N (N=C5) C=C (C) C=N6) =O) C (OC (C) C) =N4
Molecular Formula
C23H25N7O3
Molecular Weight
447.49
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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